Molecular NMR T2 values can predict cartilage stress-relaxation parameters

Correlation of T1ρ and T2 Relaxation Times Values with Glycosaminoglycan and Water Content of Articular Cartilage

T2 Relaxation Time Mapping of the Cartilage Cap of Osteochondromas

OBJECTIVE Our aim was to evaluate the cartilage cap of osteochondromas using T2 maps and to compare these values to those of normal patellar cartilage, from age and gender matched controls. MATERIALS AND METHODS This study was approved by the Institutional Review Board and request for informed consent was waived. Eleven children (ages 5-17 years) with osteochondromas underwent MR imaging, whi...

Multi-component T2* relaxation of knee cartilage under UTE acquisitions

INTRODUCTION This work reports observations of T2* relaxation in human knee cartilage explants under ultrashort echo time (UTE) acquisitions in vitro. The objective of this study was to determine the number and distribution of T2* components. We hypothesize that the three major constituents of articular cartilage extracellular matrix (water, collagen, and proteoglycan) contribute to the existen...

Cartilage MRI T2 relaxation time mapping: overview and applications.

The sensitivity of magnetic resonance imaging to biochemical and biophysical changes in the extracellular matrix of articular cartilage give it the potential to noninvasively detect the earliest changes of cartilage damage. The transverse relaxation time (T2) of cartilage has been shown to be a sensitive parameter for evaluation of early degeneration in articular cartilage, particularly changes...

T2 relaxation values in the developing preterm brain.

BACKGROUND AND PURPOSE MR imaging is increasingly used to assess maturation and disease in the preterm brain. Knowledge of the changes in T2 values with increasing postmenstrual age (PMA) will aid image interpretation and help in the objective assessment of maturation and disease of the brain in infants. The aim of this study was to obtain T2 values in the preterm brain from 25 weeks' gestation...